Iba1 anticorps (AA 1-146) (CF®740)

N° du produit ABIN7655777

L’anticorps Souris Monoclonal anti-Iba1 a été validé pour IHC et IHC (fp). Il convient pour détecter Iba1 dans des échantillons de Humain.

Aperçu rapide pour Iba1 anticorps (AA 1-146) (CF®740) (ABIN7655777)

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Iba1 est conjugé à/à la CF®740

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: AIF1-1909

Détail du produit anti-Iba1 anticorps (CF®740)

Épitope: AA 1-146

Fonction: AIF1 / Iba1 (Microglia Marker) (AIF1/1909), CF740 conjugate

Attributs du produit: Allograft Inflammatory Factor 1 (also known as AIF1 or IBA1) is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Purified fragment of human recombinant AIF1 protein (around aa 1-146)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Lymph Node, Tonsil or Kidney

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur Iba1

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Autre désignation: Allograft Inflammatory Factor 1

Sujet:

Synonyms: Allograft inflammatory factor 1, AIF1, IBA1

Gene Symbol: AIF1

Tissue Expression: Microglia|Monocytes/macrophages

Poids moléculaire: 17 kDa

ID gène: 199

UniProt: P55008

Pathways: Smooth Muscle Cell Migration